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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SH3BP5
All Species:
17.88
Human Site:
S375
Identified Species:
39.33
UniProt:
O60239
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60239
NP_004835.2
455
50425
S375
R
S
E
C
S
G
A
S
S
P
E
C
E
V
E
Chimpanzee
Pan troglodytes
XP_526142
535
58438
R467
M
F
P
V
L
G
P
R
S
E
C
S
G
A
S
Rhesus Macaque
Macaca mulatta
XP_001107738
393
43463
G325
E
G
S
S
L
G
P
G
P
A
P
D
T
D
T
Dog
Lupus familis
XP_542777
466
51639
S389
R
S
E
C
S
G
A
S
S
P
E
C
E
V
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z131
463
51788
S378
R
S
E
C
S
G
A
S
S
P
E
C
E
V
E
Rat
Rattus norvegicus
Q91Y80
457
50810
S377
R
S
E
C
S
G
A
S
S
P
E
C
E
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514506
721
77859
G652
G
P
R
S
E
C
S
G
A
S
S
P
E
C
E
Chicken
Gallus gallus
NP_001026160
431
47779
S356
R
S
E
C
S
G
A
S
S
P
E
C
E
A
E
Frog
Xenopus laevis
Q5U584
373
41573
P305
K
D
G
E
T
G
P
P
A
D
T
V
S
L
L
Zebra Danio
Brachydanio rerio
NP_998623
446
49847
P356
S
D
F
S
L
M
S
P
I
L
G
P
R
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V785
476
53619
V343
D
G
Q
Q
Q
N
D
V
W
E
H
E
L
K
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.2
34.2
87.1
N.A.
90.5
92.7
N.A.
53.5
76.4
32.5
67.2
N.A.
34.8
N.A.
N.A.
N.A.
Protein Similarity:
100
76.4
51.6
89
N.A.
93.3
94.9
N.A.
56.8
83
48.7
76.2
N.A.
50.8
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
6.6
100
N.A.
100
100
N.A.
13.3
93.3
6.6
6.6
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
6.6
100
N.A.
100
100
N.A.
26.6
93.3
33.3
13.3
N.A.
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
46
0
19
10
0
0
0
19
10
% A
% Cys:
0
0
0
46
0
10
0
0
0
0
10
46
0
10
0
% C
% Asp:
10
19
0
0
0
0
10
0
0
10
0
10
0
10
0
% D
% Glu:
10
0
46
10
10
0
0
0
0
19
46
10
55
0
64
% E
% Phe:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
19
10
0
0
73
0
19
0
0
10
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
0
0
0
0
28
0
0
0
0
10
0
0
10
10
10
% L
% Met:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
10
0
0
0
28
19
10
46
10
19
0
0
0
% P
% Gln:
0
0
10
10
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
46
0
10
0
0
0
0
10
0
0
0
0
10
0
0
% R
% Ser:
10
46
10
28
46
0
19
46
55
10
10
10
10
10
10
% S
% Thr:
0
0
0
0
10
0
0
0
0
0
10
0
10
0
10
% T
% Val:
0
0
0
10
0
0
0
10
0
0
0
10
0
37
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _